Hypoxia in Cancer

Hypoxia in cancer is a condition that arises in advanced solid tumours that has been demonstrated to lead to many complications associated with disease progression including: resistance to therapy, increased invasiveness and metastasis.

References

G. E. Lash, L-M. Postovit, N. E. Matthews, E. Y. Chung, M. T. Canning, H. Pross, M. A. Adams, and C. H. Graham.  Oxygen as a regulator of cellular phenotypes in pregnancy and cancer. Can. J. Physiol. Pharmacol. 80: 103–109 (2002)